Physiol Rev AJP: Heart and Circulatory Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiol. Rev. 79: 1373-1430, 1999;
0031-9333/99 $15.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Morris, A. J.
Right arrow Articles by Malbon, C. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Morris, A. J.
Right arrow Articles by Malbon, C. C.

Physiological Reviews, Vol. 79, No. 4, October 1999, pp. 1373-1430
Copyright ©1999 by the American Physiological Society

Physiological Regulation of G Protein-Linked Signaling

Andrew J. Morris and Craig C. Malbon

Department of Molecular Pharmacology, Diabetes and Metabolic Diseases Research Center, University Medical Center, State University of New York/Stony Brook, Stony Brook, New York

Morris, Andrew J. and Craig C. Malbon. Physiological Regulation of G Protein-Linked Signaling. J. Neurophysiol. 79: 1373-1430, 1999. Heterotrimeric G proteins in vertebrates constitute a family molecular switches that transduce the activation of a populous group of cell-surface receptors to a group of diverse effector units. The receptors include the photopigments such as rhodopsin and prominent families such as the adrenergic, muscarinic acetylcholine, and chemokine receptors involved in regulating a broad spectrum of responses in humans. Signals from receptors are sensed by heterotrimeric G proteins and transduced to effectors such as adenylyl cyclases, phospholipases, and various ion channels. Physiological regulation of G protein-linked receptors allows for integration of signals that directly or indirectly effect the signaling from receptorright-arrowG proteinright-arroweffector(s). Steroid hormones can regulate signaling via transcriptional control of the activities of the genes encoding members of G protein-linked pathways. Posttranscriptional mechanisms are under physiological control, altering the stability of preexisting mRNA and affording an additional level for regulation. Protein phosphorylation, protein prenylation, and proteolysis constitute major posttranslational mechanisms employed in the physiological regulation of G protein-linked signaling. Drawing upon mechanisms at all three levels, physiological regulation permits integration of demands placed on G protein-linked signaling.




This article has been cited by other articles:


Home page
 Mol Biol EvolHome page
S. Wadhawan, B. Dickins, and A. Nekrutenko
Wheels within Wheels: Clues to the Evolution of the Gnas and Gnal Loci
Mol. Biol. Evol., December 1, 2008; 25(12): 2745 - 2757.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
G. R Stoppa, M. Cesquini, E. A Roman, P. O Prada, A. S Torsoni, T. Romanatto, M. J Saad, L. A Velloso, and M. A Torsoni
Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling
J. Endocrinol., July 1, 2008; 198(1): 157 - 168.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
G. S. Lynch and J. G. Ryall
Role of {beta}-Adrenoceptor Signaling in Skeletal Muscle: Implications for Muscle Wasting and Disease
Physiol Rev, April 1, 2008; 88(2): 729 - 767.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. E. Kimple, J. W. Joseph, C. L. Bailey, P. T. Fueger, I. A. Hendry, C. B. Newgard, and P. J. Casey
G{alpha}z Negatively Regulates Insulin Secretion and Glucose Clearance
J. Biol. Chem., February 22, 2008; 283(8): 4560 - 4567.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
L. C. Moeller, M. Alonso, X. Liao, V. Broach, A. Dumitrescu, J. Van Sande, L. Montanelli, S. Skjei, C. Goodwin, H. Grasberger, et al.
Pituitary-Thyroid Setpoint and Thyrotropin Receptor Expression in Consomic Rats
Endocrinology, October 1, 2007; 148(10): 4727 - 4733.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Gao and H.-y. Wang
Inositol Pentakisphosphate Mediates Wnt/beta-Catenin Signaling
J. Biol. Chem., September 7, 2007; 282(36): 26490 - 26502.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Shumay, J. Tao, H.-y. Wang, and C. C. Malbon
Lysophosphatidic Acid Regulates Trafficking of beta2-Adrenergic Receptors: THE G{alpha}13/p115RhoGEF/JNK PATHWAY STIMULATES RECEPTOR INTERNALIZATION
J. Biol. Chem., July 20, 2007; 282(29): 21529 - 21541.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. Gavi, D. Yin, E. Shumay, H.-y. Wang, and C. C. Malbon
Insulin-Like Growth Factor-I Provokes Functional Antagonism and Internalization of {beta}1-Adrenergic Receptors
Endocrinology, June 1, 2007; 148(6): 2653 - 2662.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. Katayama, Y. Kusaka, H. Yokota, T. Akao, M. Kojima, O. Nakamura, E. Mekada, and E. Mizuki
Parasporin-1, a Novel Cytotoxic Protein from Bacillus thuringiensis, Induces Ca2+ Influx and a Sustained Elevation of the Cytoplasmic Ca2+ Concentration in Toxin-sensitive Cells
J. Biol. Chem., March 9, 2007; 282(10): 7742 - 7752.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. Tao, H.-y. Wang, and C. C. Malbon
Src Docks to A-kinase Anchoring Protein Gravin, Regulating beta2-Adrenergic Receptor Resensitization and Recycling
J. Biol. Chem., March 2, 2007; 282(9): 6597 - 6608.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
M. E. Sabbatini, M. S. Vatta, C. A. Davio, and L. G. Bianciotti
Atrial natriuretic factor negatively modulates secretin intracellular signaling in the exocrine pancreas
Am J Physiol Gastrointest Liver Physiol, January 1, 2007; 292(1): G349 - G357.
[Abstract] [Full Text] [PDF]

Home page
 J BiochemHome page
S. Noguchi and Y. Satow
Purification of Human {beta}2-Adrenergic Receptor Expressed in Methylotrophic Yeast Pichia pastoris
J. Biochem., December 1, 2006; 140(6): 799 - 804.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. Tao, E. Shumay, S. McLaughlin, H.-y. Wang, and C. C. Malbon
Regulation of AKAP-Membrane Interactions by Calcium
J. Biol. Chem., August 18, 2006; 281(33): 23932 - 23944.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
S. A. Lahousse, S. A. Beall, and K. J. Johnson
Mono-(2-ethylhexyl) Phthalate Rapidly Increases Celsr2 Protein Phosphorylation in HeLa Cells via Protein Kinase C and Casein Kinase 1
Toxicol. Sci., May 1, 2006; 91(1): 255 - 264.
[Abstract] [Full Text] [PDF]

Home page
 Eukaryot CellHome page
D. Dignard and M. Whiteway
SST2, a Regulator of G-Protein Signaling for the Candida albicans Mating Response Pathway
Eukaryot. Cell, January 1, 2006; 5(1): 192 - 202.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
S. Osawa, M. Kajimura, S. Yamamoto, M. Ikuma, C. Mochizuki, H. Iwasaki, A. Hishida, and S. Terakawa
Alteration of intracellular histamine H2 receptor cycling precedes antagonist-induced upregulation
Am J Physiol Gastrointest Liver Physiol, November 1, 2005; 289(5): G880 - G889.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
S. M. Assmann
G Proteins Go Green: A Plant G Protein Signaling FAQ Sheet
Science, October 7, 2005; 310(5745): 71 - 73.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J.-A. Seo, K.-H. Han, and J.-H. Yu
Multiple Roles of a Heterotrimeric G-Protein {gamma}-Subunit in Governing Growth and Development of Aspergillus nidulans
Genetics, September 1, 2005; 171(1): 81 - 89.
[Abstract] [Full Text] [PDF]

Home page
 J Biomol ScreenHome page
R. N. Ghosh, R. DeBiasio, C. C. Hudson, E. R. Ramer, C. L. Cowan, and R. H. Oakley
Quantitative Cell-Based High-Content Screening for Vasopressin Receptor Agonists Using Transfluor(R)Technology
J Biomol Screen, August 1, 2005; 10(5): 476 - 484.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
M. Frank, L. Thumer, M. J. Lohse, and M. Bunemann
G Protein Activation without Subunit Dissociation Depends on a G{alpha}i-specific Region
J. Biol. Chem., July 1, 2005; 280(26): 24584 - 24590.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
C. A. Hirshman, D. Zhu, T. Pertel, R. A. Panettieri, and C. W. Emala
Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS
Am J Physiol Lung Cell Mol Physiol, May 1, 2005; 288(5): L924 - L931.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
I. J. Arinze and Y. Kawai
Transcriptional Activation of the Human G{alpha}i2 Gene Promoter through Nuclear Factor-{kappa}B and Antioxidant Response Elements
J. Biol. Chem., March 18, 2005; 280(11): 9786 - 9795.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
Y. Zhang, M. J. Finegold, Y. Jin, and M. X. Wu
Accelerated transition from the double-positive to single-positive thymocytes in G{alpha}i2-deficient mice
Int. Immunol., March 1, 2005; 17(3): 233 - 243.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
J.-C. Zhong, D.-Y. Huang, G.-F. Liu, H.-Y. Jin, Y.-M. Yang, Y.-F. Li, X.-H. Song, and K. Du
Effects of all-trans retinoic acid on orphan receptor APJ signaling in spontaneously hypertensive rats
Cardiovasc Res, February 15, 2005; 65(3): 743 - 750.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. Gavi, D. Yin, E. Shumay, H.-y. Wang, and C. C. Malbon
The 15-Amino Acid Motif of the C Terminus of the {beta}2-Adrenergic Receptor Is Sufficient to Confer Insulin-Stimulated Counterregulation to the {beta}1-Adrenergic Receptor
Endocrinology, January 1, 2005; 146(1): 450 - 457.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y.-N. Lee, C. C. Malbon, and H.-y. Wang
G{alpha}13 Signals via p115RhoGEF Cascades Regulating JNK1 and Primitive Endoderm Formation
J. Biol. Chem., December 24, 2004; 279(52): 54896 - 54904.
[Abstract] [Full Text] [PDF]

Home page
 Sci SignalHome page
S. M. Assmann
Plant G Proteins, Phytohormones, and Plasticity: Three Questions and a Speculation
Sci. Signal., December 21, 2004; 2004(264): re20 - re20.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Liu, T. Yang, M. J. Bruno, O. S. Andersen, and S. A. Simon
Voltage-Gated Ion Channels in Nociceptors: Modulation by cGMP
J Neurophysiol, October 1, 2004; 92(4): 2323 - 2332.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
A. M. Freyer, C. K. Billington, R. B. Penn, and I. P. Hall
Extracellular Matrix Modulates {beta}2-Adrenergic Receptor Signaling in Human Airway Smooth Muscle Cells
Am. J. Respir. Cell Mol. Biol., October 1, 2004; 31(4): 440 - 445.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
Y. Uezono, M. Kaibara, O. Murasaki, and K. Taniyama
Involvement of G protein {beta}{gamma}-subunits in diverse signaling induced by Gi/o-coupled receptors: study using the Xenopus oocyte expression system
Am J Physiol Cell Physiol, October 1, 2004; 287(4): C885 - C894.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
O. Vogler, J. Casas, D. Capo, T. Nagy, G. Borchert, G. Martorell, and P. V. Escriba
The G{beta}{gamma} Dimer Drives the Interaction of Heterotrimeric Gi Proteins with Nonlamellar Membrane Structures
J. Biol. Chem., August 27, 2004; 279(35): 36540 - 36545.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. S. Popova and M. M. Rasenick
Clathrin-mediated Endocytosis of m3 Muscarinic Receptors: ROLES FOR G{beta}{gamma} AND TUBULIN
J. Biol. Chem., July 16, 2004; 279(29): 30410 - 30418.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Pharmacol.Home page
D. Yin, S. Gavi, H.-y. Wang, and C. C. Malbon
Probing Receptor Structure/Function with Chimeric G-Protein-Coupled Receptors
Mol. Pharmacol., June 1, 2004; 65(6): 1323 - 1332.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Pandey and S. M. Assmann
The Arabidopsis Putative G Protein-Coupled Receptor GCR1 Interacts with the G Protein {alpha} Subunit GPA1 and Regulates Abscisic Acid Signaling
PLANT CELL, June 1, 2004; 16(6): 1616 - 1632.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. Huang, Y. Sun, and X.-Y. Huang
Distinct Roles for Src Tyrosine Kinase in {beta}2-Adrenergic Receptor Signaling to MAPK and in Receptor Internalization
J. Biol. Chem., May 14, 2004; 279(20): 21637 - 21642.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
D. Strassheim, K. Asehnoune, J.-S. Park, J.-Y. Kim, Q. He, D. Richter, S. Mitra, J. Arcaroli, K. Kuhn, and E. Abraham
Modulation of bone marrow-derived neutrophil signaling by H2O2: disparate effects on kinases, NF-{kappa}B, and cytokine expression
Am J Physiol Cell Physiol, March 1, 2004; 286(3): C683 - C692.
[Abstract] [Full Text]

Home page
 J. Cell Sci.Home page
E. Shumay, S. Gavi, H.-y. Wang, and C. C. Malbon
Trafficking of {beta}2-adrenergic receptors: insulin and {beta}-agonists regulate internalization by distinct cytoskeletal pathways
J. Cell Sci., February 1, 2004; 117(4): 593 - 600.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
A. El-Armouche, O. Zolk, T. Rau, and T. Eschenhagen
Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure
Cardiovasc Res, December 1, 2003; 60(3): 478 - 487.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
T. T. Huang, Y. Zong, H. Dalwadi, C. Chung, M. C. Miceli, K. Spicher, L. Birnbaumer, J. Braun, and R. Aranda
TCR-mediated hyper-responsiveness of autoimmune G{alpha}i2-/- mice is an intrinsic naive CD4+ T cell disorder selective for the G{alpha}i2 subunit
Int. Immunol., November 1, 2003; 15(11): 1359 - 1367.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. S. Popova and M. M. Rasenick
G{beta}{gamma} Mediates the Interplay between Tubulin Dimers and Microtubules in the Modulation of Gq Signaling
J. Biol. Chem., September 5, 2003; 278(36): 34299 - 34308.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. Hou, K. Suzuki, W. J. Wolfgang, C. Clay, M. Forte, and Y. Kidokoro
Presynaptic Impairment of Synaptic Transmission in Drosophila Embryos Lacking Gs{alpha}
J. Neurosci., July 2, 2003; 23(13): 5897 - 5905.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Z. Liu, L. Geng, R. Li, X. He, J. Q. Zheng, and Z. Xie
Frequency Modulation of Synchronized Ca2+ Spikes in Cultured Hippocampal Networks through G-Protein-Coupled Receptors
J. Neurosci., May 15, 2003; 23(10): 4156 - 4163.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
H. Dalwadi, B. Wei, M. Schrage, T. T. Su, D. J. Rawlings, and J. Braun
B Cell Developmental Requirement for the G{alpha}i2 Gene
J. Immunol., February 15, 2003; 170(4): 1707 - 1715.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
A. Ahumada, D. C. Slusarski, X. Liu, R. T. Moon, C. C. Malbon, and H.-y. Wang
Signaling of Rat Frizzled-2 Through Phosphodiesterase and Cyclic GMP
Science, December 6, 2002; 298(5600): 2006 - 2010.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Mochizuki, B. Brassart, and A. Hinek
Signaling Pathways Transduced through the Elastin Receptor Facilitate Proliferation of Arterial Smooth Muscle Cells
J. Biol. Chem., November 15, 2002; 277(47): 44854 - 44863.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
E. Shumay, X. Song, H.-y. Wang, and C. C. Malbon
pp60Src Mediates Insulin-stimulated Sequestration of the beta 2-Adrenergic Receptor: Insulin Stimulates pp60Src Phosphorylation and Activation
Mol. Biol. Cell, November 1, 2002; 13(11): 3943 - 3954.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
Z.-Q. Cheng, D. Bose, H. Jacobs, R Bruce Light, and S. N Mink
Sepsis causes presynaptic histamine H3 and {alpha}2-adrenergic dysfunction in canine myocardium
Cardiovasc Res, November 1, 2002; 56(2): 225 - 234.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
K. L. Chambliss and P. W. Shaul
Estrogen Modulation of Endothelial Nitric Oxide Synthase
Endocr. Rev., October 1, 2002; 23(5): 665 - 686.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
O. Oldenburg, Q. Qin, A. R Sharma, M. V Cohen, J. M Downey, and J. N Benoit
Acetylcholine leads to free radical production dependent on KATP channels, Gi proteins, phosphatidylinositol 3-kinase and tyrosine kinase
Cardiovasc Res, August 15, 2002; 55(3): 544 - 552.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
X.-P. Huang, X. Song, H.-Y. Wang, and C. C. Malbon
Targeted expression of activated Q227L Galpha s in vivo
Am J Physiol Cell Physiol, August 1, 2002; 283(2): C386 - C395.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
L. Voisin, S. Foisy, E. Giasson, C. Lambert, P. Moreau, and S. Meloche
EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors
Am J Physiol Cell Physiol, August 1, 2002; 283(2): C446 - C455.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
J. E. Dumont, S. Dremier, I. Pirson, and C. Maenhaut
Cross signaling, cell specificity, and physiology
Am J Physiol Cell Physiol, July 1, 2002; 283(1): C2 - C28.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. Bertram, M. I. Arnot, and G. W. Zamponi
Role for G Protein Gbeta gamma Isoform Specificity in Synaptic Signal Processing: A Computational Study
J Neurophysiol, May 1, 2002; 87(5): 2612 - 2623.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. M. Assmann
Heterotrimeric and Unconventional GTP Binding Proteins in Plant Cell Signaling
PLANT CELL, May 1, 2002; 14(90001): S355 - 373.
[Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Doronin, E. Shumay, H.-y. Wang, and C. C. Malbon
Akt Mediates Sequestration of the beta 2-Adrenergic Receptor in Response to Insulin
J. Biol. Chem., April 19, 2002; 277(17): 15124 - 15131.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
G. Smits, C. Govaerts, I. Nubourgh, L. Pardo, G. Vassart, and S. Costagliola
Lysine 183 and Glutamic Acid 157 of the TSH Receptor: Two Interacting Residues with a Key Role in Determining Specificity toward TSH and Human CG
Mol. Endocrinol., April 1, 2002; 16(4): 722 - 735.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
V. Vlaeminck-Guillem, S.-C. Ho, P. Rodien, G. Vassart, and S. Costagliola
Activation of the cAMP Pathway by the TSH Receptor Involves Switching of the Ectodomain from a Tethered Inverse Agonist to an Agonist
Mol. Endocrinol., April 1, 2002; 16(4): 736 - 746.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Doronin, H.-y. Wang, and C. C. Malbon
Insulin Stimulates Phosphorylation of the beta 2-Adrenergic Receptor by the Insulin Receptor, Creating a Potent Feedback Inhibitor of Its Tyrosine Kinase
J. Biol. Chem., March 15, 2002; 277(12): 10698 - 10703.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H.-y. Wang, J. Kanungo, and C. C. Malbon
Expression of Galpha 13 (Q226L) Induces P19 Stem Cells to Primitive Endoderm via MEKK1, 2, or 4
J. Biol. Chem., January 25, 2002; 277(5): 3530 - 3536.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
H. S. Kang, D. Kerstan, L.-J. Dai, G. Ritchie, and G. A. Quamme
Adenosine modulates Mg2+ uptake in distal convoluted tubule cells via A1 and A2 purinoceptors
Am J Physiol Renal Physiol, December 1, 2001; 281(6): F1141 - F1147.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
B. Zheng, Y.-C. Ma, R. S. Ostrom, C. Lavoie, G. N. Gill, P. A. Insel, X.-Y. Huang, and M. G. Farquhar
RGS-PX1, a GAP for Galpha s and Sorting Nexin in Vesicular Trafficking
Science, November 30, 2001; 294(5548): 1939 - 1942.
[Abstract] [Full Text]