Physiol Rev Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiol. Rev. 86: 1033-1048, 2006; doi:10.1152/physrev.00030.2005
0031-9333/06 $18.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (45)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dan, Y.
Right arrow Articles by Poo, M.-M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dan, Y.
Right arrow Articles by Poo, M.-M.

Spike Timing-Dependent Plasticity: From Synapse to Perception

Yang Dan and Mu-Ming Poo

Division of Neurobiology, Department of Molecular and Cell Biology, and Helen Wills Neuroscience Institute, University of California, Berkeley, California

Information in the nervous system may be carried by both the rate and timing of neuronal spikes. Recent findings of spike timing-dependent plasticity (STDP) have fueled the interest in the potential roles of spike timing in processing and storage of information in neural circuits. Induction of long-term potentiation (LTP) and long-term depression (LTD) in a variety of in vitro and in vivo systems has been shown to depend on the temporal order of pre- and postsynaptic spiking. Spike timing-dependent modification of neuronal excitability and dendritic integration was also observed. Such STDP at the synaptic and cellular level is likely to play important roles in activity-induced functional changes in neuronal receptive fields and human perception.




This article has been cited by other articles:


Home page
 NeuroscientistHome page
R. Corlew, D. J. Brasier, D. E. Feldman, and B. D. Philpot
Presynaptic NMDA Receptors: Newly Appreciated Roles in Cortical Synaptic Function and Plasticity
Neuroscientist, December 1, 2008; 14(6): 609 - 625.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
D. D. Cox and J. J. DiCarlo
Does Learned Shape Selectivity in Inferior Temporal Cortex Automatically Generalize Across Retinal Position?
J. Neurosci., October 1, 2008; 28(40): 10045 - 10055.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
G. Stocca, C. Schmidt-Hieber, and J. Bischofberger
Differential dendritic Ca2+ signalling in young and mature hippocampal granule cells
J. Physiol., August 15, 2008; 586(16): 3795 - 3811.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. Lee, W.-M. Zhu, D. Stanic, D. I. Finkelstein, M. H. Horne, J. Henderson, A. J. Lawrence, L. O'Connor, D. Tomas, J. Drago, et al.
Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinaesia
Brain, June 1, 2008; 131(6): 1574 - 1587.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
P.-P. Lenck-Santini and G. L. Holmes
Altered Phase Precession and Compression of Temporal Sequences by Place Cells in Epileptic Rats
J. Neurosci., May 7, 2008; 28(19): 5053 - 5062.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
P. J. Sjostrom, E. A. Rancz, A. Roth, and M. Hausser
Dendritic Excitability and Synaptic Plasticity
Physiol Rev, April 1, 2008; 88(2): 769 - 840.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
J.-i. Tanaka, Y. Horiike, M. Matsuzaki, T. Miyazaki, G. C. R. Ellis-Davies, and H. Kasai
Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines
Science, March 21, 2008; 319(5870): 1683 - 1687.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
E. Campanac and D. Debanne
Spike timing-dependent plasticity: a learning rule for dendritic integration in rat CA1 pyramidal neurons
J. Physiol., February 1, 2008; 586(3): 779 - 793.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
E. Fino, J.-M. Deniau, and L. Venance
Cell-specific spike-timing-dependent plasticity in GABAergic and cholinergic interneurons in corticostriatal rat brain slices
J. Physiol., January 1, 2008; 586(1): 265 - 282.
[Abstract] [Full Text] [PDF]

Home page
 Adaptive BehaviorHome page
P. Phattanasri, H. J. Chiel, and R. D. Beer
The Dynamics of Associative Learning in Evolved Model Circuits
Adaptive Behavior, December 1, 2007; 15(4): 377 - 396.
[Abstract] [PDF]

Home page
 J. Physiol.Home page
K. A. Buchanan and J. R. Mellor
The development of synaptic plasticity induction rules and the requirement for postsynaptic spikes in rat hippocampal CA1 pyramidal neurones
J. Physiol., December 1, 2007; 585(2): 429 - 445.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. Kyriakatos and A. El Manira
Long-Term Plasticity of the Spinal Locomotor Circuitry Mediated by Endocannabinoid and Nitric Oxide Signaling
J. Neurosci., November 14, 2007; 27(46): 12664 - 12674.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Fuenzalida, D. Fernandez de Sevilla, and W. Buno
Changes of the EPSP Waveform Regulate the Temporal Window for Spike-Timing-Dependent Plasticity
J. Neurosci., October 31, 2007; 27(44): 11940 - 11948.
[Abstract] [Full Text] [PDF]

Home page
 Chem SensesHome page
A. Young and Q.-Q. Sun
Long-Term Modifications in the Strength of Excitatory Associative Inputs in the Piriform Cortex
Chem Senses, October 1, 2007; 32(8): 783 - 794.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
R. Corlew, Y. Wang, H. Ghermazien, A. Erisir, and B. D. Philpot
Developmental Switch in the Contribution of Presynaptic and Postsynaptic NMDA Receptors to Long-Term Depression
J. Neurosci., September 12, 2007; 27(37): 9835 - 9845.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J.-t. Lu, C.-y. Li, J.-P. Zhao, M.-m. Poo, and X.-h. Zhang
Spike-Timing-Dependent Plasticity of Neocortical Excitatory Synapses on Inhibitory Interneurons Depends on Target Cell Type
J. Neurosci., September 5, 2007; 27(36): 9711 - 9720.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
W. J. Tyler, G. C. Petzold, S. K. Pal, and V. N. Murthy
Experience-Dependent Modification of Primary Sensory Synapses in the Mammalian Olfactory Bulb
J. Neurosci., August 29, 2007; 27(35): 9427 - 9438.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. L. Rathbun, H. J. Alitto, T. G. Weyand, and W. M. Usrey
Interspike Interval Analysis of Retinal Ganglion Cell Receptive Fields
J Neurophysiol, August 1, 2007; 98(2): 911 - 919.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
F. D. Roy, J. A. Norton, and M. A. Gorassini
Role of Sustained Excitability of the Leg Motor Cortex After Transcranial Magnetic Stimulation in Associative Plasticity
J Neurophysiol, August 1, 2007; 98(2): 657 - 667.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Chen, J. D. Bohanick, M. Nishihara, J. K. Seamans, and C. R. Yang
Dopamine D1/5 Receptor-Mediated Long-Term Potentiation of Intrinsic Excitability in Rat Prefrontal Cortical Neurons: Ca2+-Dependent Intracellular Signaling
J Neurophysiol, March 1, 2007; 97(3): 2448 - 2464.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
V. Jacob, D. J. Brasier, I. Erchova, D. Feldman, and D. E. Shulz
Spike Timing-Dependent Synaptic Depression in the In Vivo Barrel Cortex of the Rat
J. Neurosci., February 7, 2007; 27(6): 1271 - 1284.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2006 by the American Physiological Society.