Phys. Rev. -- Table of Contents (October 2007, 87, (4))

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Robert A. Fenton and Mark A. Knepper: Mouse Models and the Urinary Concentrating Mechanism in the New Millennium
Physiol. Rev. 87: 1083-1112, 2007; doi:10.1152/physrev.00053.2006 [Abstract] [Full Text] [PDF]

Ewelina Knapska, Kasia Radwanska, Tomasz Werka, and Leszek Kaczmarek: Functional Internal Complexity of Amygdala: Focus on Gene Activity Mapping After Behavioral Training and Drugs of Abuse
Physiol. Rev. 87: 1113-1173, 2007; doi:10.1152/physrev.00037.2006 [Abstract] [Full Text] [PDF]

A. J. Hulbert, Reinald Pamplona, Rochelle Buffenstein, and W. A. Buttemer: Life and Death: Metabolic Rate, Membrane Composition, and Life Span of Animals
Physiol. Rev. 87: 1175-1213, 2007; doi:10.1152/physrev.00047.2006 [Abstract] [Full Text] [PDF]

Yehezkel Ben-Ari, Jean-Luc Gaiarsa, Roman Tyzio, and Rustem Khazipov: GABA: A Pioneer Transmitter That Excites Immature Neurons and Generates Primitive Oscillations
Physiol. Rev. 87: 1215-1284, 2007; doi:10.1152/physrev.00017.2006 [Abstract] [Full Text] [PDF]

Francis G. Spinale: Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
Physiol. Rev. 87: 1285-1342, 2007; doi:10.1152/physrev.00012.2007 [Abstract] [Full Text] [PDF]

Gijs R. van den Brink: Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract
Physiol. Rev. 87: 1343-1375, 2007; doi:10.1152/physrev.00054.2006 [Abstract] [Full Text] [PDF]

Daniel N. Hebert and Maurizio Molinari: In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases
Physiol. Rev. 87: 1377-1408, 2007; doi:10.1152/physrev.00050.2006 [Abstract] [Full Text] [PDF]

Jens Juul Holst: The Physiology of Glucagon-like Peptide 1
Physiol. Rev. 87: 1409-1439, 2007; doi:10.1152/physrev.00034.2006 [Abstract] [Full Text] [PDF]

Maurice B. Burg, Joan D. Ferraris, and Natalia I. Dmitrieva: Cellular Response to Hyperosmotic Stresses
Physiol. Rev. 87: 1441-1474, 2007; doi:10.1152/physrev.00056.2006 [Abstract] [Full Text] [PDF]

Cover

Cover: Life and death: why do different species vary so greatly in their maximum possible life span? Why can humans live for up to 120 years yet rats live only 3 years? Why are birds so long living? What are the mechanisms that determine the distinctive maximum life span for each species? These questions have long puzzled biologists. Early answers were related to metabolic intensity of different species, yet it has been known for a while that the rate-of-living theory was not a complete explanation. In recent years it has become apparent that the fatty acid composition of membranes varies systematically among species and that when the different membrane composition is combined with the oxidative-stress theory, much of the variation in maximum life span among different animal species can be explained. See Hulbert, A. J., Reinald Pamplona, Rochelle Buffenstein, and W. A. Buttemer. Physiol Rev 87: 1175-1213, 2007.